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Abstract—Radio resource management mechanisms such asPHY-centric Radio Resource Allocation and MAC-centricPacket Scheduling are expected to play a substantial role in theperformance of future OFDMA-based wireless networks.Inevitably, efficient resource allocation strategies have toexploit information laying in different OSI layers, allowing for across-layer design. In the literature adaptive allocation schemeshave been proposed for optimum or suboptimum resourcedistribution in the frequency domain under static individual userrate constraints. The contribution of this work is twofold: First,we evaluate current allocation schemes under realistic trafficand channel conditions, in order to acquire the upperperformance bounds on a real time evolving network. Then weextend them to incorporate MAC-layer information, as well asopportunistic packet scheduling in the time-domain. The keyfactors that affect the overall system performance in terms ofsystem average throughput and delay are identified, evaluatedand discussed. The presented ideas are accompanied withextensive system level Monte-Carlo simulations. Index Terms—OFDMA, Resource Allocation, Packetscheduling, multiuser OFDM, cross-layer Cite: A. G. Gotsis, N. Th. Koutsokeras, and Prof. Ph. Constantinou, "PHY- and MAC-aware Resource Allocation and Packet Scheduling for Single-Cell OFDMA Packet Networks," Journal of Communications, vol. 3, no.4, September, pp. 59-70, 2008.